I'll split this post into two parts, rail-related and non-rail-related. Rail related New York is home to the most utilized rail station in the country, Penn Station, and arguably the most beautiful rail station in the country (Grand Central Terminal, served only by Metro North commuter trains). Both are located in the heart of Midtown. The subway in New York runs all day, every day. The fare is a flat $2.25 (as of now), and you can go almost anywhere in the city once you board. Be sure to study the map beforehand, as it is quite confusing to most. In terms of museums, NY offers an excellent transit museum, with historic artifacts, displays, a functioning control tower, and 23 vintage subway cars. It is located in Downtown Brooklyn, easily reachable via approximately a dozen train routes. Wiki page Official website - hours and directions Non rail related NY offers a wide range of cultural attractions, monuments, and other interesting places. The major museums include: Metropolitan Museum of Art: pretty much every type of art you can think of is displayed here, from an Egyptian pyramid to Impressionism to baseball cards. Guggenheim Museum: art museum with the famous spiral design. Museum of Modern Art: a museum dedicated to American Museum of Natural History: huge museum covering every aspect of the history of the world. It features an excellent planetarium and collection of dinosaur bones, among numerous other exhibits. Intrepid Sea-Air-Space Museum: a museum of military air and naval history. Includes a real aircraft carrier (USS Intrepid), a submarine that once housed nuclear weapons (USS Growler), and the same Concorde that flew from New York to London in less than 3 hours. Other attractions include: Bronx Zoo: a 265-acre zoo with over 4,000 animals. It includes a monorail that travels through additional exhibits not accessible to pedestrians. New York Hall of Science: a museum dedicated to science. Carnegie Hall: excellent music and concert venue. Radio City Music Hall: excellent music and concert venue. Lincoln Center: collection of opera, theater, and music centers. Statue of Liberty: one of the most recognizable symbols of NY. While it has been difficult to see the statue up close in recent years, an excellent alternative is the free Staten Island Ferry (departs from the South Ferry subway station), which passes close by. The ferry is a one-hour round trip. Ellis Island: see the place where millions of immigrants passed through on their way to America. World Trade Center: the memorial here is set to open on the attacks' 10th anniversary. Useful Links include: Subway Weekender: this website helps with planning your journeys around town on weekends, as most weekends have extensive construction work going on around town. Note that weekends are NOT the only time that changes take place; see the MTA site (link below) for details. The official MTA website: the official site of the NYC transportation agency. Check this site out for everything related to the subway, bus, LIRR, and MNRR. Note: I'll keep this post updated as much as possible.