I am told even the operating crews (conductors/engineers) don't have any keys for the padlocks.
I don't think that is accurate, I recall reading somewhere that someone was able to obtain some medicine that had been accidentally left in a car during the trip. Wish I could remember where I read it...
Perhaps, during the utility stop in Florence, where some of the locals there might have keys? That's the only place they might have time for any searching. I couldn't see them stopping/delaying the train en-route to search for one car out of hundreds to find a medicine bottle. First, they'd need to know which auto carrier it (the target car) is in. I know they keep records of when a car gets loaded/unloaded, but do they also record the specific auto carrier # into which it's loaded? Then, they'd have to find that auto carrier out of 18+ and hope they can find that particular car in the auto carrier. And with the ramps folded up, I'm not it's even possible to get to the "upper deckers."
Probably would be more effective for Amtrak to call a pharmacy in Florence and have the meds waiting there at the utility stop.